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Lessons Learned from the First Decade of Laser-Assisted Drug Delivery
Laser-assisted drug delivery augments the distribution and penetration of topically applied treatments, leading to enhanced delivery and bioavailability. We discuss the therapeutic application of laser-assisted drug delivery in clinical practice in cases of non-melanoma skin cancer, vitiligo, melasm...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858718/ https://www.ncbi.nlm.nih.gov/pubmed/33464473 http://dx.doi.org/10.1007/s13555-020-00478-5 |
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author | Searle, Tamara Ali, Faisal R. Al-Niaimi, Firas |
author_facet | Searle, Tamara Ali, Faisal R. Al-Niaimi, Firas |
author_sort | Searle, Tamara |
collection | PubMed |
description | Laser-assisted drug delivery augments the distribution and penetration of topically applied treatments, leading to enhanced delivery and bioavailability. We discuss the therapeutic application of laser-assisted drug delivery in clinical practice in cases of non-melanoma skin cancer, vitiligo, melasma, scarring, and alopecia (female pattern hair loss, male pattern hair loss, alopecia areata) as well as for vaccination, local anaesthesia, analgesia, viral warts, infantile haemangiomas and cosmetic uses, and we review clinical studies that have used this technique over the last decade. Our review shows that the application of laser-assisted drug delivery enhances topical agent efficacy, potentially reducing the agent concentration and duration of topical treatment required. Future research into the use of laser-assisted drug delivery before topical therapies is needed to establish the optimal techniques to enhance drug delivery and thus improve patient outcomes. |
format | Online Article Text |
id | pubmed-7858718 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Healthcare |
record_format | MEDLINE/PubMed |
spelling | pubmed-78587182021-02-11 Lessons Learned from the First Decade of Laser-Assisted Drug Delivery Searle, Tamara Ali, Faisal R. Al-Niaimi, Firas Dermatol Ther (Heidelb) Review Laser-assisted drug delivery augments the distribution and penetration of topically applied treatments, leading to enhanced delivery and bioavailability. We discuss the therapeutic application of laser-assisted drug delivery in clinical practice in cases of non-melanoma skin cancer, vitiligo, melasma, scarring, and alopecia (female pattern hair loss, male pattern hair loss, alopecia areata) as well as for vaccination, local anaesthesia, analgesia, viral warts, infantile haemangiomas and cosmetic uses, and we review clinical studies that have used this technique over the last decade. Our review shows that the application of laser-assisted drug delivery enhances topical agent efficacy, potentially reducing the agent concentration and duration of topical treatment required. Future research into the use of laser-assisted drug delivery before topical therapies is needed to establish the optimal techniques to enhance drug delivery and thus improve patient outcomes. Springer Healthcare 2021-01-19 /pmc/articles/PMC7858718/ /pubmed/33464473 http://dx.doi.org/10.1007/s13555-020-00478-5 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Review Searle, Tamara Ali, Faisal R. Al-Niaimi, Firas Lessons Learned from the First Decade of Laser-Assisted Drug Delivery |
title | Lessons Learned from the First Decade of Laser-Assisted Drug Delivery |
title_full | Lessons Learned from the First Decade of Laser-Assisted Drug Delivery |
title_fullStr | Lessons Learned from the First Decade of Laser-Assisted Drug Delivery |
title_full_unstemmed | Lessons Learned from the First Decade of Laser-Assisted Drug Delivery |
title_short | Lessons Learned from the First Decade of Laser-Assisted Drug Delivery |
title_sort | lessons learned from the first decade of laser-assisted drug delivery |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858718/ https://www.ncbi.nlm.nih.gov/pubmed/33464473 http://dx.doi.org/10.1007/s13555-020-00478-5 |
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