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Obesity reduces the anticancer effect of AdipoRon against orthotopic pancreatic cancer in diet-induced obese mice

The antidiabetic adiponectin receptor agonist AdipoRon has been shown to suppress the tumour growth of human pancreatic cancer cells. Because obesity and diabetes affect pancreatic cancer progression and chemoresistance, we investigated the effect of AdipoRon on orthotopic tumour growth of Panc02 pa...

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Detalles Bibliográficos
Autores principales:	Takenaga, Keizo, Akimoto, Miho, Koshikawa, Nobuko, Nagase, Hiroki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859201/ https://www.ncbi.nlm.nih.gov/pubmed/33536560 http://dx.doi.org/10.1038/s41598-021-82617-2

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