CD39(+)PD-1(+)CD8(+) T cells mediate metastatic dormancy in breast cancer

Some breast tumors metastasize aggressively whereas others remain dormant for years. The mechanism governing metastatic dormancy remains largely unknown. Through high-parametric single-cell mapping in mice, we identify a discrete population of CD39(+)PD-1(+)CD8(+) T cells in primary tumors and in do...

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Detalles Bibliográficos
Autores principales: Tallón de Lara, Paulino, Castañón, Héctor, Vermeer, Marijne, Núñez, Nicolás, Silina, Karina, Sobottka, Bettina, Urdinez, Joaquín, Cecconi, Virginia, Yagita, Hideo, Movahedian Attar, Farkhondeh, Hiltbrunner, Stefanie, Glarner, Isabelle, Moch, Holger, Tugues, Sònia, Becher, Burkhard, van den Broek, Maries
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859213/
https://www.ncbi.nlm.nih.gov/pubmed/33536445
http://dx.doi.org/10.1038/s41467-021-21045-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859213/
https://www.ncbi.nlm.nih.gov/pubmed/33536445
http://dx.doi.org/10.1038/s41467-021-21045-2

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