Cargando…

Subchondral Bone Remodeling: A Therapeutic Target for Osteoarthritis

There is emerging awareness that subchondral bone remodeling plays an important role in the development of osteoarthritis (OA). This review presents recent investigations on the cellular and molecular mechanism of subchondral bone remodeling, and summarizes the current interventions and potential th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Xiaobo, Chan, Yau Tsz, Yung, Patrick S. H., Tuan, Rocky S., Jiang, Yangzi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859330/ https://www.ncbi.nlm.nih.gov/pubmed/33553146 http://dx.doi.org/10.3389/fcell.2020.607764

Ejemplares similares

Subchondral bone remodelling and osteoarthritis
por: Román-Blas, Jorge A, et al.
Publicado: (2012)

Subchondral bone remodelling in osteoarthritis
por: Donell, Simon
Publicado: (2019)

Macrophage polarization in osteoarthritis progression: a promising therapeutic target
por: Zhang, Yanlei, et al.
Publicado: (2023)

Histone Modifications and Chondrocyte Fate: Regulation and Therapeutic Implications
por: Wan, Chao, et al.
Publicado: (2021)

Chondrocyte-like cells in nucleus pulposus and articular chondrocytes have similar transcriptomic profiles and are paracrine-regulated by hedgehog from notochordal cells and subchondral bone
por: Hagizawa, Hiroki, et al.
Publicado: (2023)

Communications Between Bone Marrow Macrophages and Bone Cells in Bone Remodeling
por: Chen, Kaixuan, et al.
Publicado: (2020)

The Role of Sphingolipid Metabolism in Bone Remodeling
por: Qi, Tang, et al.
Publicado: (2021)

ORAI1 Ca(2+) Channel as a Therapeutic Target in Pathological Vascular Remodelling
por: Shawer, Heba, et al.
Publicado: (2021)

Targeting subchondral bone in osteoporotic osteoarthritis
por: Roman-Blas, Jorge A, et al.
Publicado: (2014)

Dihydroartemisinin attenuates osteoarthritis by inhibiting abnormal bone remodeling and angiogenesis in subchondral bone
por: Ma, Long, et al.
Publicado: (2021)

Editorial: Novel Therapies for Combating Bone Diseases Through Advances in Bone Remodeling
por: Jiao, Yurui, et al.
Publicado: (2021)

Bone Angiogenesis and Vascular Niche Remodeling in Stress, Aging, and Diseases
por: Stucker, Sina, et al.
Publicado: (2020)

Blood Vessels and Vascular Niches in Bone Development and Physiological Remodeling
por: Hendriks, Michelle, et al.
Publicado: (2020)

m6A Methylation Regulates Osteoblastic Differentiation and Bone Remodeling
por: Huang, Mei, et al.
Publicado: (2021)

Parathyroid hormone attenuates osteoarthritis pain by remodeling subchondral bone in mice
por: Sun, Qi, et al.
Publicado: (2021)

Therapeutic effects of different intervention forms of human umbilical cord mesenchymal stem cells in the treatment of osteoarthritis
por: Zhang, Yuelong, et al.
Publicado: (2023)

Bone-Derived Modulators That Regulate Brain Function: Emerging Therapeutic Targets for Neurological Disorders
por: Chen, Hongzhen, et al.
Publicado: (2021)

Targeting Cell Death: Pyroptosis, Ferroptosis, Apoptosis and Necroptosis in Osteoarthritis
por: Yang, Jian, et al.
Publicado: (2022)

Halofuginone Attenuates Osteoarthritis by Rescuing Bone Remodeling in Subchondral Bone Through Oral Gavage
por: Mu, Wenbo, et al.
Publicado: (2018)

Monocyte/Macrophage Lineage Cells From Fetal Erythromyeloid Progenitors Orchestrate Bone Remodeling and Repair
por: Yahara, Yasuhito, et al.
Publicado: (2021)

Although Anatomically Micrometers Apart: Human Periodontal Ligament Cells Are Slightly More Active in Bone Remodeling Than Alveolar Bone Derived Cells
por: Loo-Kirana, Rebecca, et al.
Publicado: (2021)

RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7
por: Cheng, Jin, et al.
Publicado: (2021)

Molecular Classification of Knee Osteoarthritis
por: Lv, Zhongyang, et al.
Publicado: (2021)

Mechanistic Insight Into the Roles of Integrins in Osteoarthritis
por: Jin, Hongfu, et al.
Publicado: (2021)

Ferroptosis, a Potential Therapeutic Target in Alzheimer’s Disease
por: Chen, Kai, et al.
Publicado: (2021)

Potential of Soluble Decellularized Extracellular Matrix for Musculoskeletal Tissue Engineering – Comparison of Various Mesenchymal Tissues
por: Hanai, Hiroto, et al.
Publicado: (2020)

Osteoclasts secrete leukemia inhibitory factor to promote abnormal bone remodeling of subchondral bone in osteoarthritis
por: Zhao, Xin, et al.
Publicado: (2022)

Endoplasmic Reticulum-Mitochondria Contacts: A Potential Therapy Target for Cardiovascular Remodeling-Associated Diseases
por: Wang, Yu, et al.
Publicado: (2021)

Osteocytic HIF-1α Pathway Manipulates Bone Micro-structure and Remodeling via Regulating Osteocyte Terminal Differentiation
por: Chen, Kaizhe, et al.
Publicado: (2022)

Macrophage, a potential targeted therapeutic immune cell for cardiomyopathy
por: Chen, Ganyi, et al.
Publicado: (2022)

Subchondral bone architecture and quality in osteoarthritis
por: Aspden, RM
Publicado: (2004)

The Importance of Subchondral Bone in the Pathophysiology of Osteoarthritis
por: Stewart, Holly L., et al.
Publicado: (2018)

Subchondral bone histology and grading in osteoarthritis
por: Aho, Olli-Matti, et al.
Publicado: (2017)

Subchondral bone microenvironment in osteoarthritis and pain
por: Hu, Yan, et al.
Publicado: (2021)

The Role of Autophagy in Osteoarthritis
por: Duan, Ran, et al.
Publicado: (2020)

Cell Interplay in Osteoarthritis
por: Li, Zihao, et al.
Publicado: (2021)

Role of adiponectin in osteoarthritis
por: Feng, Xinyuan, et al.
Publicado: (2022)

HO-1 in Bone Biology: Potential Therapeutic Strategies for Osteoporosis
por: Zhou, Xueman, et al.
Publicado: (2021)

Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis
por: Bellido, Miriam, et al.
Publicado: (2010)

Calcium-phosphate complex increased during subchondral bone remodeling affects earlystage osteoarthritis
por: Jung, Youn-Kwan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_h10omf767v2iu25ag5imn85tuo