LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma

Leucine zipper/EF hand-containing transmembrane-1 (LETM1) is an inner mitochondrial membrane protein that has been reported to be involved in many primary tumors and may regulate many biological processes. However, the biological role and molecular mechanism of LETM1 in the progression of hepatocell...

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Detalles Bibliográficos
Autores principales: Zhou, Baoyong, Yang, Changhong, Yan, Xiong, Shi, Zhengrong, Xiao, Heng, Wei, Xufu, Jiang, Ning, Wu, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859436/
https://www.ncbi.nlm.nih.gov/pubmed/33552978
http://dx.doi.org/10.3389/fonc.2020.606790

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