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YAP Activation and Implications in Patients and a Mouse Model of Biliary Atresia

Background and Aim: Biliary atresia (BA), an inflammatory destruction of the bile ducts, leads to liver fibrosis in infants and accounts for half of cases undergoing pediatric liver transplantation. Yes-associated protein (YAP), an effector of the Hippo signaling pathway, is critical in maintaining...

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Detalles Bibliográficos
Autores principales: Zheng, Chao, Luo, Jiaqian, Yang, Yifan, Dong, Rui, Yu, Fa-Xing, Zheng, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859521/
https://www.ncbi.nlm.nih.gov/pubmed/33553074
http://dx.doi.org/10.3389/fped.2020.618226