Cargando…
MeCP2: The Genetic Driver of Rett Syndrome Epigenetics
Mutations in methyl CpG binding protein 2 (MeCP2) are the major cause of Rett syndrome (RTT), a rare neurodevelopmental disorder with a notable period of developmental regression following apparently normal initial development. Such MeCP2 alterations often result in changes to DNA binding and chroma...
Autores principales: | Good, Katrina V., Vincent, John B., Ausió, Juan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859524/ https://www.ncbi.nlm.nih.gov/pubmed/33552148 http://dx.doi.org/10.3389/fgene.2021.620859 |
Ejemplares similares
-
The Molecular Functions of MeCP2 in Rett Syndrome Pathology
por: Sharifi, Osman, et al.
Publicado: (2021) -
Rett Syndrome and MECP2 Duplication Syndrome: Disorders of MeCP2 Dosage
por: Collins, Bridget E, et al.
Publicado: (2022) -
Novel alterations in the epigenetic signature of MeCP2-targeted promoters in lymphocytes of Rett syndrome patients
por: Lilja, Tobias, et al.
Publicado: (2013) -
Structural investigation of Rett-inducing MeCP2 mutations()
por: Spiga, Ottavia, et al.
Publicado: (2018) -
Rett mutations attenuate phase separation of MeCP2
por: Fan, Chunyan, et al.
Publicado: (2020)