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Muffin Technique Micrographic Surgery for Non-melanoma Skin Cancer
Background: Mohs micrographic surgery (MMS) is the gold standard treatment for high-risk facial non-melanoma skin cancer. However, patients' access to MMS is limited by cost. The muffin technique micrographic surgery (MTMS) is an alternative micrographic technique wherein the entire excised mar...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859636/ https://www.ncbi.nlm.nih.gov/pubmed/33553223 http://dx.doi.org/10.3389/fmed.2020.637223 |
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author | Surmanowicz, Philip Sivanand, Arunima Du, Amy X. Mahmood, Muhammad N. Gniadecki, Robert |
author_facet | Surmanowicz, Philip Sivanand, Arunima Du, Amy X. Mahmood, Muhammad N. Gniadecki, Robert |
author_sort | Surmanowicz, Philip |
collection | PubMed |
description | Background: Mohs micrographic surgery (MMS) is the gold standard treatment for high-risk facial non-melanoma skin cancer. However, patients' access to MMS is limited by cost. The muffin technique micrographic surgery (MTMS) is an alternative micrographic technique wherein the entire excised margin is evaluated post-operatively by a pathologist using paraffin-embedded material. Herein, we describe the implementation and the preliminary results of MTMS in an academic dermatology center. Objective: To describe the MTMS and outline its efficacy and safety in a real-world clinical academic setting. Methods: A retrospective chart review was conducted of all patients with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) who underwent MTMS at the University of Alberta Dermatology Center from June 2016 until July 2019. Results: A total of 69 patients were included (64 BCCs and 5 SCCs). 68.1% of surgeries had clear margins following the first incision, 100% after second round re-excisions. There were no observed cases of tumor recurrence after a median 40 months of follow-up. There were no major adverse events or complications. Conclusions: MTMS is a superior alternative to simple excision of skin cancer by providing full margin control and residual tumor mapping. |
format | Online Article Text |
id | pubmed-7859636 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78596362021-02-05 Muffin Technique Micrographic Surgery for Non-melanoma Skin Cancer Surmanowicz, Philip Sivanand, Arunima Du, Amy X. Mahmood, Muhammad N. Gniadecki, Robert Front Med (Lausanne) Medicine Background: Mohs micrographic surgery (MMS) is the gold standard treatment for high-risk facial non-melanoma skin cancer. However, patients' access to MMS is limited by cost. The muffin technique micrographic surgery (MTMS) is an alternative micrographic technique wherein the entire excised margin is evaluated post-operatively by a pathologist using paraffin-embedded material. Herein, we describe the implementation and the preliminary results of MTMS in an academic dermatology center. Objective: To describe the MTMS and outline its efficacy and safety in a real-world clinical academic setting. Methods: A retrospective chart review was conducted of all patients with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) who underwent MTMS at the University of Alberta Dermatology Center from June 2016 until July 2019. Results: A total of 69 patients were included (64 BCCs and 5 SCCs). 68.1% of surgeries had clear margins following the first incision, 100% after second round re-excisions. There were no observed cases of tumor recurrence after a median 40 months of follow-up. There were no major adverse events or complications. Conclusions: MTMS is a superior alternative to simple excision of skin cancer by providing full margin control and residual tumor mapping. Frontiers Media S.A. 2021-01-21 /pmc/articles/PMC7859636/ /pubmed/33553223 http://dx.doi.org/10.3389/fmed.2020.637223 Text en Copyright © 2021 Surmanowicz, Sivanand, Du, Mahmood and Gniadecki. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Surmanowicz, Philip Sivanand, Arunima Du, Amy X. Mahmood, Muhammad N. Gniadecki, Robert Muffin Technique Micrographic Surgery for Non-melanoma Skin Cancer |
title | Muffin Technique Micrographic Surgery for Non-melanoma Skin Cancer |
title_full | Muffin Technique Micrographic Surgery for Non-melanoma Skin Cancer |
title_fullStr | Muffin Technique Micrographic Surgery for Non-melanoma Skin Cancer |
title_full_unstemmed | Muffin Technique Micrographic Surgery for Non-melanoma Skin Cancer |
title_short | Muffin Technique Micrographic Surgery for Non-melanoma Skin Cancer |
title_sort | muffin technique micrographic surgery for non-melanoma skin cancer |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859636/ https://www.ncbi.nlm.nih.gov/pubmed/33553223 http://dx.doi.org/10.3389/fmed.2020.637223 |
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