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The emergence of various genetic alterations mediated the Osimertinib resistance of a patient harboring heterozygous germline EGFR T790M: a case report

Epidermal growth factor receptor (EGFR) T790M is the major mechanism mediating resistance to first- and second-generation EGFR tyrosine kinase inhibitors. Despite the high frequency of EGFR activating mutations among East Asian lung cancer patients, germline T790M has been the subject of very little...

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Detalles Bibliográficos
Autores principales:	Liu, Bin, Qin, Jianwen, Yin, Yan, Zhai, Liang, Liu, Guangxin, Lizaso, Analyn, Shi, Dongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859814/ https://www.ncbi.nlm.nih.gov/pubmed/33553373 http://dx.doi.org/10.21037/atm-20-7626

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