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rHDL modeling and the anchoring mechanism of LCAT activation

Lecithin:cholesterol-acyl transferase (LCAT) plays a major role in cholesterol metabolism as it is the only extracellular enzyme able to esterify cholesterol. LCAT activity is required for lipoprotein remodeling and, most specifically, for the growth and maturation of HDLs. In fact, genetic alterati...

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Detalles Bibliográficos
Autores principales:	Laurenzi, Tommaso, Parravicini, Chiara, Palazzolo, Luca, Guerrini, Uliano, Gianazza, Elisabetta, Calabresi, Laura, Eberini, Ivano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859856/ https://www.ncbi.nlm.nih.gov/pubmed/33518511 http://dx.doi.org/10.1194/jlr.RA120000843

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