Cargando…

MicroRNA-34a-5p serves as a tumor suppressor by regulating the cell motility of bladder cancer cells through matrix metalloproteinase-2 silencing

Bladder cancer (BC), a common urologic cancer, is the fifth most frequently diagnosed tumor worldwide. hsa-miR-34a displays antitumor activity in several types of cancer. However, the functional mechanisms underlying hsa-miR-34a in BC remains largely unknown. We observed that hsa-mir-34a levels were...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chou, Kuang-Yu, Chang, An-Chen, Tsai, Te-Fu, Lin, Yi-Chia, Chen, Hung-En, Ho, Chao-Yen, Chen, Po-Chun, Hwang, Thomas I-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859909/ https://www.ncbi.nlm.nih.gov/pubmed/33650650 http://dx.doi.org/10.3892/or.2020.7910

Ejemplares similares

Tumor suppressive functions of hsa-miR-34a on cell cycle, migration and protective autophagy in bladder cancer
por: Hwang, Thomas I-Sheng, et al.
Publicado: (2023)

Fluid-induced, shear stress-regulated extracellular matrix and matrix metalloproteinase genes expression on human annulus fibrosus cells
por: Chou, Po-Hsin, et al.
Publicado: (2016)

Thrombospondin‐4 promotes bladder cancer cell migration and invasion via MMP2 production
por: Chou, Kuang‐Yu, et al.
Publicado: (2021)

Effects of RNA silencing of matrix metalloproteinase-2 on the growth of esophageal carcinoma cells in vivo
por: Shen, Yu-Guang, et al.
Publicado: (2017)

Miconazole Contributes to NRF2 Activation by Noncanonical P62-KEAP1 Pathway in Bladder Cancer Cells
por: Tsai, Te-Fu, et al.
Publicado: (2020)

Matrix Metalloproteinases and Bladder Cancer: What is New?
por: Rodriguez Faba, O., et al.
Publicado: (2012)

Inhibition of cyclooxygenase-2 decreases breast cancer cell motility, invasion and matrix metalloproteinase expression
por: Larkins, Teri L, et al.
Publicado: (2006)

Galectin-3 increases the motility of mouse melanoma cells by regulating matrix metalloproteinase-1 expression
por: Wang, Yuan-Guo, et al.
Publicado: (2012)

miR-99a-5p acts as tumor suppressor via targeting to mTOR and enhances RAD001-induced apoptosis in human urinary bladder urothelial carcinoma cells
por: Tsai, Te-Fu, et al.
Publicado: (2018)

Matrix metalloproteinase-7 may serve as a novel biomarker for cervical cancer
por: Zhu, Linyan, et al.
Publicado: (2018)

Haloperidol Abrogates Matrix Metalloproteinase-9 Expression by Inhibition of NF-κB Activation in Stimulated Human Monocytic Cells
por: Lee, Yueh-Lun, et al.
Publicado: (2018)

By activating matrix metalloproteinase-7, shear stress promotes chondrosarcoma cell motility, invasion and lung colonization
por: Guan, Pei-Pei, et al.
Publicado: (2015)

Elevated matrix metalloproteinase 7 expression promotes the proliferation, motility and metastasis of tongue squamous cell carcinoma
por: Yuan, Shuo, et al.
Publicado: (2020)

Matrix Metalloproteinase 11 is a Potential Biomarker in Bladder Cancer Diagnosis and Prognosis
por: Chen, Chen, et al.
Publicado: (2020)

Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development
por: Raza, Qanber S., et al.
Publicado: (2017)

Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in the hair cycle
por: HOU, CHUN, et al.
Publicado: (2016)

Overexpression of carbonic anhydrase IX induces cell motility by activating matrix metalloproteinase-9 in human oral squamous cell carcinoma cells
por: Yang, Jia-Sin, et al.
Publicado: (2017)

Hsa-miR-30a-3p overcomes the acquired protective autophagy of bladder cancer in chemotherapy and suppresses tumor growth and muscle invasion
por: Hwang, Thomas I-Sheng, et al.
Publicado: (2022)

AB169. CCDC34 is up-regulated in bladder cancer and its silencing suppresses bladder cancer cell proliferation and migration
por: Gong, Yanqing, et al.
Publicado: (2015)

Correction: Hsa-miR-30a-3p overcomes the acquired protective autophagy of bladder cancer in chemotherapy and suppresses tumor growth and muscle invasion
por: Hwang, Thomas I-Sheng, et al.
Publicado: (2022)

The Significance of Matrix Metalloproteinase 9 (MMP-9) and Metalloproteinase 2 (MMP-2) in Urinary Bladder Cancer
por: Kudelski, Jacek, et al.
Publicado: (2023)

Cisplatin induces protective autophagy through activation of BECN1 in human bladder cancer cells
por: Lin, Ji-Fan, et al.
Publicado: (2017)

Prognostic role of matrix metalloproteinases in bladder carcinoma: a systematic review and meta-analysis
por: Miao, Chenkui, et al.
Publicado: (2017)

Decreased Invasion of Urothelial Carcinoma of the Bladder by Inhibition of Matrix-Metalloproteinase 7
por: Bolenz, Christian, et al.
Publicado: (2018)

Cisplatin contributes to programmed death-ligand 1 expression in bladder cancer through ERK1/2-AP-1 signaling pathway
por: Tsai, Te-Fu, et al.
Publicado: (2019)

An E3 Ubiquitin Ligase RNF139 Serves as a Tumor-Suppressor in Glioma
por: Chen, Xiaofeng, et al.
Publicado: (2021)

Matrix Metalloproteinase-1 Polymorphism (-1607G) and Disease Severity in Non-Cystic Fibrosis Bronchiectasis in Taiwan
por: Hsieh, Meng-Heng, et al.
Publicado: (2013)

Snail silences suppressor
por: Maxmen, Amy
Publicado: (2009)

The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway
por: Kuo, Jean-Cheng, et al.
Publicado: (2006)

Downregulation of miR-106b induced breast cancer cell invasion and motility in association with overexpression of matrix metalloproteinase 2
por: Ni, Xiaojian, et al.
Publicado: (2014)

Inhibition of CD34+ cell migration by matrix metalloproteinase-2 during acute myocardial ischemia, counteracted by ischemic preconditioning
por: Lukovic, Dominika, et al.
Publicado: (2017)

Mechanisms of cartilage matrix turnover: synergistic interactions of proinflammatory cytokines with oncostatin M in upregulating matrix metalloproteinases and ADAMTS metalloproteinases
por: Cawston, TE, et al.
Publicado: (2005)

The Coat Protein of Citrus Yellow Vein Clearing Virus Interacts with Viral Movement Proteins and Serves as an RNA Silencing Suppressor
por: Rehman, Atta Ur, et al.
Publicado: (2019)

Inhibition of cell invasion and migration by targeting matrix metalloproteinase-9 expression via sirtuin 6 silencing in human breast cancer cells
por: Hong, On-Yu, et al.
Publicado: (2022)

Interplay of N-Cadherin and matrix metalloproteinase 9 enhances human nasopharyngeal carcinoma cell invasion
por: Hsu, Chih-Chin, et al.
Publicado: (2016)

Autophagy inhibition enhances RAD001-induced cytotoxicity in human bladder cancer cells
por: Lin, Ji-Fan, et al.
Publicado: (2016)

The Novel HDAC8 Inhibitor WK2-16 Attenuates Lipopolysaccharide-Activated Matrix Metalloproteinase-9 Expression in Human Monocytic Cells and Improves Hypercytokinemia In Vivo
por: Jan, Jing-Shiun, et al.
Publicado: (2017)

ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14
por: Guo, Danfeng, et al.
Publicado: (2022)

Clusterin Silencing in Prostate Cancer Induces Matrix Metalloproteinases by an NF-κB-Dependent Mechanism
por: Bonacini, Martina, et al.
Publicado: (2019)

Epigallocatechin-3-gallate inhibits migration and invasion of human renal carcinoma cells by downregulating matrix metalloproteinase-2 and matrix metalloproteinase-9
por: CHEN, SHAO-JUN, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_tqsvqngjbv3onihic5pcgsk0ke