Comprehensive analysis of genomic mutation signature and tumor mutation burden for prognosis of intrahepatic cholangiocarcinoma

BACKGROUND: Intrahepatic cholangiocarcinoma (iCCA) is a highly lethal malignancy of the biliary tract. Analysis of somatic mutational profiling can reveal new prognostic markers and actionable treatment targets. In this study, we explored the utility of genomic mutation signature and tumor mutation...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Li, Qi, Fu, Jialu, Jin, Zhechuan, Su, Jingbo, Zhang, Jian, Chen, Chen, Geng, Zhimin, Zhang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860034/
https://www.ncbi.nlm.nih.gov/pubmed/33535978
http://dx.doi.org/10.1186/s12885-021-07788-7

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