Cargando…

Preclinical Pharmacokinetic Interaction and Histopathological Analyses of Hedyotis diffusa on Sorafenib in Rats

[Image: see text] Sorafenib is one of the most effective target therapeutic agents for patients with late-stage hepatocellular carcinoma. To seek possible alternative adjuvant agents to enhance the efficacy and improve the side effect of sorafenib, Hedyotis diffusa, one of the most prescribed phytom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ting, Chin-Tsung, Cheng, Yung-Yi, Tsai, Tung-Hu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860071/ https://www.ncbi.nlm.nih.gov/pubmed/33553923 http://dx.doi.org/10.1021/acsomega.0c05461

Ejemplares similares

Herb-Drug Interaction between the Traditional Hepatoprotective Formulation and Sorafenib on Hepatotoxicity, Histopathology and Pharmacokinetics in Rats
por: Ting, Chin-Tsung, et al.
Publicado: (2017)

The Antitumor Constituents from Hedyotis Diffusa Willd
por: Wang, Changfu, et al.
Publicado: (2017)

Mechanism of Hedyotis Diffusa in the Treatment of Cervical Cancer
por: Qian, Kai, et al.
Publicado: (2021)

Chemical Constituents of Hedyotis diffusa and Their Anti-Inflammatory Bioactivities
por: Hung, Hsin-Yi, et al.
Publicado: (2022)

The Hedyotis diffusa Willd. (Rubiaceae): A Review on Phytochemistry, Pharmacology, Quality Control and Pharmacokinetics
por: Chen, Rui, et al.
Publicado: (2016)

Discovery of the Potential Biomarkers for Discrimination between Hedyotis diffusa and Hedyotis corymbosa by UPLC-QTOF/MS Metabolome Analysis
por: Wang, Yaru, et al.
Publicado: (2018)

Exploring the mechanism of action of Hedyotis diffusa Willd on acne using network analysis
por: Seo, Gwangyeel, et al.
Publicado: (2023)

Inhibitory effects of total triterpenoids isolated from the Hedyotis diffusa willd on H1975 cells
por: Wu, Kenan, et al.
Publicado: (2022)

Metabolic regulations of a decoction of Hedyotis diffusa in acute liver injury of mouse models
por: Dai, Min, et al.
Publicado: (2017)

Molecular Mechanism of Anti-Colorectal Cancer Effect of Hedyotis diffusa Willd and Its Extracts
por: Wu, Zihong, et al.
Publicado: (2022)

Molecular mechanism of Hedyotis Diffusae Herba in the treatment of lupus nephritis based on network pharmacology
por: Yang, Jinfei, et al.
Publicado: (2023)

Network Pharmacology Analysis and Experimental Verification on Antiangiogenesis Mechanism of Hedyotis diffusa Willd in Liver Cancer
por: Wu, Hongyan, et al.
Publicado: (2023)

Chemical Profiles and Protective Effect of Hedyotis diffusa Willd in Lipopolysaccharide-Induced Renal Inflammation Mice
por: Ye, Jian-Hong, et al.
Publicado: (2015)

Therapeutic effects of Hedyotis diffusa Willd in a COPD mouse model challenged with LPS and smoke
por: Liu, Renping, et al.
Publicado: (2018)

A Network Pharmacology Approach to Uncover the Multiple Mechanisms of Hedyotis diffusa Willd. on Colorectal Cancer
por: Liu, Xinkui, et al.
Publicado: (2018)

Network Pharmacology-Based Approach to Investigate the Mechanisms of Hedyotis diffusa Willd. in the Treatment of Gastric Cancer
por: Liu, Xinkui, et al.
Publicado: (2018)

Differentiation of Hedyotis diffusa and Common Adulterants Based on Chloroplast Genome Sequencing and DNA Barcoding Markers
por: Yik, Mavis Hong-Yu, et al.
Publicado: (2021)

Hedyotis diffusa Willd. Suppresses Hepatocellular Carcinoma via Downregulating AKT/mTOR Pathways
por: Huang, Lingli, et al.
Publicado: (2021)

Protective Effect of Hedyotis diffusa Willd. Ethanol Extract on Isoniazid-Induced Liver Injury in the Zebrafish Model
por: Wang, Xin, et al.
Publicado: (2022)

Network pharmacology and experimental validation to identify the potential mechanism of Hedyotis diffusa Willd against rheumatoid arthritis
por: Deng, Hui, et al.
Publicado: (2023)

Hedyotis diffusa Willd Inhibits Colorectal Cancer Growth in Vivo via Inhibition of STAT3 Signaling Pathway
por: Cai, Qiaoyan, et al.
Publicado: (2012)

Mitigation of Aflatoxin B(1) Hepatoxicity by Dietary Hedyotis diffusa Is Associated with Activation of NRF2/ARE Signaling in Chicks
por: Zhao, Ling, et al.
Publicado: (2021)

The protective capability of Hedyotis diffusa Willd on lupus nephritis by attenuating the IL-17 expression in MRL/lpr mice
por: Li, Ying, et al.
Publicado: (2022)

Determination of Oleanolic and Ursolic Acids in Hedyotis diffusa Using Hyphenated Ultrasound-Assisted Supercritical Carbon Dioxide Extraction and Chromatography
por: Wei, Ming-Chi, et al.
Publicado: (2015)

Synergistic inhibition of leukemia WEHI-3 cell growth by arsenic trioxide and Hedyotis diffusa Willd extract in vitro and in vivo
por: Kuo, Yu-Jui, et al.
Publicado: (2017)

Investigating the Multi-Target Pharmacological Mechanism of Hedyotis diffusa Willd Acting on Prostate Cancer: A Network Pharmacology Approach
por: Song, Yanan, et al.
Publicado: (2019)

Preclinical Pharmacokinetics and Pharmacodynamics of Coptidis Preparation in Combination with Lovastatin in High-Fat Diet-Induced Hyperlipidemic Rats
por: Peng, Wen-Ya, et al.
Publicado: (2021)

Bioassay-Guided Isolation of Anti-Alzheimer Active Components from the Aerial Parts of Hedyotis diffusa and Simultaneous Analysis for Marker Compounds
por: Park, Jun Hee, et al.
Publicado: (2020)

Ethyl Acetate Fraction of Hedyotis diffusa Willd Induces Apoptosis via JNK/Nur77 Pathway in Hepatocellular Carcinoma Cells
por: Ning, Weimin, et al.
Publicado: (2022)

Molecular Targets and Mechanisms of Hedyotis diffusa-Scutellaria barbata Herb Pair for the Treatment of Colorectal Cancer Based on Network Pharmacology and Molecular Docking
por: Yang, Zhenpeng, et al.
Publicado: (2022)

Preclinical Pharmacokinetics of Lamivudine and Its Interaction with Schisandra chinensis Extract in Rats
por: Li, Chi-Lin, et al.
Publicado: (2020)

Hedyotis diffusa Combined with Scutellaria barbata Are the Core Treatment of Chinese Herbal Medicine Used for Breast Cancer Patients: A Population-Based Study
por: Yeh, Yuan-Chieh, et al.
Publicado: (2014)

Antioxidant effect of aqueous extract of four plants with therapeutic potential on gynecological diseases; Semen persicae, Leonurus cardiaca, Hedyotis diffusa, and Curcuma zedoaria
por: Ji, Shaojian, et al.
Publicado: (2017)

Pharmacokinetic Interaction between Sorafenib and Atorvastatin, and Sorafenib and Metformin in Rats
por: Karbownik, Agnieszka, et al.
Publicado: (2020)

Hedyotis diffusa plus Scutellaria barbata Induce Bladder Cancer Cell Apoptosis by Inhibiting Akt Signaling Pathway through Downregulating miR-155 Expression
por: Pan, Li-Tao, et al.
Publicado: (2016)

Hedyotis diffusa Willd. extract suppresses proliferation and induces apoptosis via IL-6-inducible STAT3 pathway inactivation in human colorectal cancer cells
por: LIN, JIUMAO, et al.
Publicado: (2015)

Novel Antiviral Efficacy of Hedyotis diffusa and Artemisia capillaris Extracts against Dengue Virus, Japanese Encephalitis Virus, and Zika Virus Infection and Immunoregulatory Cytokine Signatures
por: Mao, Zhan Qiu, et al.
Publicado: (2022)

Preclinical Herb–Drug Pharmacokinetic Interaction of Panax ginseng Extract and Selegiline in Freely Moving Rats
por: Yang, Ling, et al.
Publicado: (2020)

Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Exerts Anti-Inflammatory Effects by Regulating miR-155 Expression and JNK Signaling Pathway
por: Xu, Yuan, et al.
Publicado: (2018)

Hedyotis diffusa plus Scutellaria barbata Suppress the Growth of Non-Small-Cell Lung Cancer via NLRP3/NF-κB/MAPK Signaling Pathways
por: Lv, Ya-Xin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_km37h90mpf69m5n7f20r0f5qf4