A stem cell based in vitro model of NAFLD enables the analysis of patient specific individual metabolic adaptations in response to a high fat diet and AdipoRon interference

Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease. Its development and progression depend on genetically predisposed susceptibility of the patient towards several ‘hits’ that induce fat storage first and later inflammation and fibrosis. Here, we differentiated induced pluripotent...

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Detalles Bibliográficos
Autores principales: Graffmann, Nina, Ncube, Audrey, Martins, Soraia, Fiszl, Aurelian Robert, Reuther, Philipp, Bohndorf, Martina, Wruck, Wasco, Beller, Mathias, Czekelius, Constantin, Adjaye, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860118/
https://www.ncbi.nlm.nih.gov/pubmed/33372064
http://dx.doi.org/10.1242/bio.054189

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