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Changes in epigenetic profiles throughout early childhood and their relationship to the response to pneumococcal vaccination
BACKGROUND: Pneumococcal infections are a major cause of morbidity and mortality in young children and immaturity of the immune system partly underlies poor vaccine responses seen in the young. Emerging evidence suggests a key role for epigenetics in the maturation and regulation of the immune syste...
Autores principales: | Pischedda, Sara, O’Connor, Daniel, Fairfax, Benjamin P., Salas, Antonio, Martinon-Torres, Federico, Pollard, Andrew J., Trück, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860179/ https://www.ncbi.nlm.nih.gov/pubmed/33541404 http://dx.doi.org/10.1186/s13148-021-01012-w |
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