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Improved prediction of fracture risk leveraging a genome-wide polygenic risk score

BACKGROUND: Accurately quantifying the risk of osteoporotic fracture is important for directing appropriate clinical interventions. While skeletal measures such as heel quantitative speed of sound (SOS) and dual-energy X-ray absorptiometry bone mineral density are able to predict the risk of osteopo...

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Detalles Bibliográficos
Autores principales:	Lu, Tianyuan, Forgetta, Vincenzo, Keller-Baruch, Julyan, Nethander, Maria, Bennett, Derrick, Forest, Marie, Bhatnagar, Sahir, Walters, Robin G., Lin, Kuang, Chen, Zhengming, Li, Liming, Karlsson, Magnus, Mellström, Dan, Orwoll, Eric, McCloskey, Eugene V., Kanis, John A., Leslie, William D., Clarke, Robert J., Ohlsson, Claes, Greenwood, Celia M. T., Richards, J. Brent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860212/ https://www.ncbi.nlm.nih.gov/pubmed/33536041 http://dx.doi.org/10.1186/s13073-021-00838-6

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