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KAT6A regulates stemness of aging bone marrow-derived mesenchymal stem cells through Nrf2/ARE signaling pathway

BACKGROUND: This study aimed to explore the effect of KAT6A on the decreased stemness of aging bone marrow-derived mesenchymal stem cells (BMSCs) and its potential mechanism. METHODS: The acetylation level and KAT6A expression of BMSCs from the young (YBMSCs) and the old (OBMSCs) were examined. Gain...

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Detalles Bibliográficos
Autores principales: Fei, Dongdong, Wang, Yazheng, Zhai, Qiming, Zhang, Xige, Zhang, Yang, Wang, Yang, Li, Bei, Wang, Qintao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860225/
https://www.ncbi.nlm.nih.gov/pubmed/33541408
http://dx.doi.org/10.1186/s13287-021-02164-5

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