Cargando…

Multiomic analysis identifies natural intrapatient temporal variability and changes in response to systemic corticosteroid therapy in chronic rhinosinusitis

INTRODUCTION: The pathophysiology and temporal dynamics of affected tissues in chronic rhinosinusitis (CRS) remain poorly understood. Here, we present a multiomics‐based time‐series assessment of nasal polyp biopsies from three patients with CRS, assessing natural variability over time and local res...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hoggard, Michael, Jacob, Bincy, Wheeler, David, Zoing, Melissa, Chang, Kevin, Biswas, Kristi, Middleditch, Martin, Douglas, Richard G., Taylor, Michael W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860613/ https://www.ncbi.nlm.nih.gov/pubmed/33220024 http://dx.doi.org/10.1002/iid3.349

Ejemplares similares

Differentially Regulated Host Proteins Associated with Chronic Rhinosinusitis Are Correlated with the Sinonasal Microbiome
por: Biswas, Kristi, et al.
Publicado: (2017)

Inflammatory Endotypes and Microbial Associations in Chronic Rhinosinusitis
por: Hoggard, Michael, et al.
Publicado: (2018)

Antibiotic Treatment for Chronic Rhinosinusitis: Prescription Patterns and Associations With Patient Outcome and the Sinus Microbiota
por: Lux, Christian A., et al.
Publicado: (2020)

Characterising clinical Staphylococcus aureus isolates from the sinuses of patients with chronic rhinosinusitis
por: Wagner Mackenzie, Brett, et al.
Publicado: (2021)

Longitudinal analysis of sinus microbiota post endoscopic surgery in patients with cystic fibrosis and chronic rhinosinusitis: a pilot study
por: Wagner Mackenzie, Brett, et al.
Publicado: (2021)

Longitudinal study of the bacterial and fungal microbiota in the human sinuses reveals seasonal and annual changes in diversity
por: Wagner Mackenzie, Brett, et al.
Publicado: (2019)

Comparison of Subtyping Approaches and the Underlying Drivers of Microbial Signatures for Chronic Rhinosinusitis
por: Biswas, Kristi, et al.
Publicado: (2019)

Intrapatient variability in plasma rifampicin & isoniazid in tuberculosis patients
por: Kumar, A. K. Hemanth, et al.
Publicado: (2018)

Retrospective Analysis of Tacrolimus Intrapatient Variability as a Measure of Medication Adherence
por: Herblum, Jordana, et al.
Publicado: (2021)

Clinical Implications of Tacrolimus Time in Therapeutic Range and Intrapatient Variability in Urban Renal Transplant Recipients Undergoing Early Corticosteroid Withdrawal
por: Pierce, Dana R., et al.
Publicado: (2021)

Intrapatient variability of 18F-FDG uptake in normal tissues
por: Sayed, Mohamed Hosny Mohamed, et al.
Publicado: (2022)

OR23-01 Intrapatient ACTH Variability in Cushing’s Disease: Prognostic Significance
por: Alvarez, Reinier, et al.
Publicado: (2020)

High intrapatient variability of tacrolimus exposure associated with poorer outcomes in liver transplantation
por: Dopazo, Cristina, et al.
Publicado: (2022)

Non-invasive assessment of inter-and intrapatient variability of integrin expression in metastasized prostate cancer by PET
por: Beer, Ambros J., et al.
Publicado: (2016)

Comparing Azole Plasma Trough Levels in Lung Transplant Recipients: Percentage of Therapeutic Levels and Intrapatient Variability
por: Stelzer, Daniela, et al.
Publicado: (2017)

The nasal microbiota in health and disease: variation within and between subjects
por: Biswas, Kristi, et al.
Publicado: (2015)

Safety of intranasal corticosteroids in acute rhinosinusitis
por: Demoly, Pascal
Publicado: (2008)

Interval Safety Layer Coupled With an Impulsive MPC for Artificial Pancreas to Handle Intrapatient Variability
por: Villa-Tamayo, María F., et al.
Publicado: (2022)

High Tacrolimus Intrapatient Variability and Subtherapeutic Immunosuppression are Associated With Adverse Kidney Transplant Outcomes
por: Mendoza Rojas, Aleixandra, et al.
Publicado: (2022)

Population genomics of intrapatient HIV-1 evolution
por: Zanini, Fabio, et al.
Publicado: (2015)

Intrapatient competition of VEXAS syndrome and CML clones
por: Djerbi, Nadia, et al.
Publicado: (2023)

A Novel Description of the Human Sinus Archaeome During Health and Chronic Rhinosinusitis
por: Wagner Mackenzie, Brett, et al.
Publicado: (2020)

High Calcineurin Inhibitor Intrapatient Variability Is Associated With Renal Allograft Inflammation, Chronicity, and Graft Loss
por: Sharma, Akhil, et al.
Publicado: (2019)

Association of Intrapatient Variability of Tacrolimus Concentration With Early Deterioration of Chronic Histologic Lesions in Kidney Transplantation
por: Mo, Hyejin, et al.
Publicado: (2019)

Sinonasal Tissue Remodelling during Chronic Rhinosinusitis
por: Amirapu, Satya, et al.
Publicado: (2021)

Number of Regularly Prescribed Drugs and Intrapatient Tacrolimus Trough Levels Variability in Stable Kidney Transplant Recipients
por: Giza, Piotr, et al.
Publicado: (2020)

Association between medication adherence and intrapatient variability in tacrolimus concentration among stable kidney transplant recipients
por: Ko, Hyunmin, et al.
Publicado: (2021)

The DNA methylation landscape of multiple myeloma shows extensive inter- and intrapatient heterogeneity that fuels transcriptomic variability
por: Derrien, Jennifer, et al.
Publicado: (2021)

Evidence of Recombination in Intrapatient Populations of Hepatitis C Virus
por: Sentandreu, Vicente, et al.
Publicado: (2008)

High Intrapatient Variability of Tacrolimus Levels and Outpatient Clinic Nonattendance Are Associated With Inferior Outcomes in Renal Transplant Patients
por: Goodall, Dawn L., et al.
Publicado: (2017)

Long-term intrapatient evolution during HIV-2 infection
por: MacNeil, Adam, et al.
Publicado: (2006)

CancerTracer: a curated database for intrapatient tumor heterogeneity
por: Wang, Chen, et al.
Publicado: (2020)

Evaluation of capillary density in psoriasis: An intrapatient study and literature review
por: Micali, Giuseppe, et al.
Publicado: (2021)

Reduced Local Response to Corticosteroids in Eosinophilic Chronic Rhinosinusitis with Asthma
por: Kobayashi, Yoshiki, et al.
Publicado: (2020)

Systemic corticosteroids in treatment of chronic rhinosinusitis—A systematic review
por: Tamene, Sarah, et al.
Publicado: (2023)

Intrapatient Variability in Tacrolimus Trough Levels Over 2 Years Affects Long-Term Allograft Outcomes of Kidney Transplantation
por: Park, Yohan, et al.
Publicado: (2021)

Tacrolimus Intrapatient Variability After Switching From Immediate or Prolonged-Release to Extended-Release Formulation, After an Organ Transplantation
por: Del Bello, Arnaud, et al.
Publicado: (2021)

Characterizing the Human Mycobiota: A Comparison of Small Subunit rRNA, ITS1, ITS2, and Large Subunit rRNA Genomic Targets
por: Hoggard, Michael, et al.
Publicado: (2018)

Comparison of Corticosteroids by 3 Approaches to the Treatment of Chronic Rhinosinusitis With Nasal Polyps
por: Zhang, Yunyun, et al.
Publicado: (2019)

The Effect of Corticosteroids on Sinus Microbiota in Chronic Rhinosinusitis Patients with Nasal Polyposis
por: Alammar, Yousif, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_a9n87oag10rmjd2uahe0ceouo9