Investigation of Heterochromatin Protein 1 Function in the Malaria Parasite Plasmodium falciparum Using a Conditional Domain Deletion and Swapping Approach

The human malaria parasite Plasmodium falciparum encodes a single ortholog of heterochromatin protein 1 (PfHP1) that plays a crucial role in the epigenetic regulation of various survival-related processes. PfHP1 is essential for parasite proliferation and the heritable silencing of genes linked to a...

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Detalles Bibliográficos
Autores principales: Bui, Hai T. N., Passecker, Armin, Brancucci, Nicolas M. B., Voss, Till S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7860992/
https://www.ncbi.nlm.nih.gov/pubmed/33536327
http://dx.doi.org/10.1128/mSphere.01220-20

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