Whole exome sequencing reveals pathogenic variants in MYO3A, MYO15A and COL9A3 and differential frequencies in ancestral alleles in hearing impairment genes among individuals from Cameroon

There is scarcity of known gene variants of hearing impairment (HI) in African populations. This knowledge deficit is ultimately affecting the development of genetic diagnoses. We used whole exome sequencing to investigate gene variants, pathways of interactive genes and the fractions of ancestral o...

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Detalles Bibliográficos
Autores principales: Wonkam, Ambroise, Manyisa, Noluthando, Bope, Christian D, Dandara, Collet, Chimusa, Emile R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861016/
https://www.ncbi.nlm.nih.gov/pubmed/33078831
http://dx.doi.org/10.1093/hmg/ddaa225

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