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Regulatory Master Genes Identification and Drug Repositioning by Integrative mRNA-miRNA Network Analysis for Acute Type A Aortic Dissection

Acute type A aortic dissection (ATAAD) is a life-threatening disease. The understanding of its pathogenesis and treatment approaches remains unclear. In the present work, differentially expressed genes (DEGs) from two ATAAD datasets GSE52093 and GSE98770 were filtered. Transcription factor TEAD4 was...

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Detalles Bibliográficos
Autores principales: Fang, Junjun, Pan, Zongfu, Yu, Hao, Yang, Si, Hu, Xiaoping, Lu, Xiaoyang, Li, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861055/
https://www.ncbi.nlm.nih.gov/pubmed/33551796
http://dx.doi.org/10.3389/fphar.2020.575765