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RAC1 controls progressive movement and competitiveness of mammalian spermatozoa

Mammalian spermatozoa employ calcium (Ca(2+)) and cyclic adenosine monophosphate (cAMP) signaling in generating flagellar beat. However, how sperm direct their movement towards the egg cells has remained elusive. Here we show that the Rho small G protein RAC1 plays an important role in controlling p...

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Detalles Bibliográficos
Autores principales: Amaral, Alexandra, Herrmann, Bernhard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861394/
https://www.ncbi.nlm.nih.gov/pubmed/33539343
http://dx.doi.org/10.1371/journal.pgen.1009308