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The regulation of Hypoxia-Inducible Factor-1 (HIF-1alpha) expression by Protein Disulfide Isomerase (PDI)

Hypoxia-inducible factor-1alpha (HIF-1alpha), a transcription factor, plays a critical role in adaption to hypoxia, which is a major feature of diseases, including cancer. Protein disulfide isomerase (PDI) is up-regulated in numerous cancers and leads to cancer progression. PDI, a member of the TRX...

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Detalles Bibliográficos
Autores principales:	Kobayashi, Yukino, Oguro, Ami, Hirata, Yuta, Imaoka, Susumu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861413/ https://www.ncbi.nlm.nih.gov/pubmed/33539422 http://dx.doi.org/10.1371/journal.pone.0246531

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