Cargando…

Intratumorally CpG immunotherapy with carbon nanotubes inhibits local tumor growth and liver metastasis by suppressing the epithelial–mesenchymal transition of colon cancer cells

Colon cancer liver metastasis accounts for the major cause of death of colon cancer patients. Previous study reported a carbon nanotubes (CNT)-conjugated CpG complex (CNT-CpG), which displayed a significant antitumor effect in gliomas. However, whether CNT-CpG could limit colon tumor growth and supp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Hongyong, Gao, Sujie, Song, Defeng, Liu, Yiting, Chen, Xuebo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Preclinical Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861496/ https://www.ncbi.nlm.nih.gov/pubmed/32976213 http://dx.doi.org/10.1097/CAD.0000000000001000

Ejemplares similares

MAGEC2, an epithelial-mesenchymal transition inducer, is associated with breast cancer metastasis
por: Yang, Fan, et al.
Publicado: (2014)

Metronomic Doses of Temozolomide Enhance the Efficacy of Carbon Nanotube CpG Immunotherapy in an Invasive Glioma Model
por: Ouyang, Mao, et al.
Publicado: (2016)

Rosthorin A inhibits non-small cell lung cancer cell growth and metastasis through repressing epithelial-mesenchymal transition via downregulating Slug
por: Ni, Lulu, et al.
Publicado: (2020)

Epithelial-to-mesenchymal transition status of primary breast carcinomas and its correlation with metastatic behavior
por: Savci-Heijink, C. D., et al.
Publicado: (2019)

CpG-Based Nanovaccines for Cancer Immunotherapy
por: Chen, Wenqiang, et al.
Publicado: (2021)

Helicobacter pylori CagA Protein Attenuates 5-Fu Sensitivity of Gastric Cancer Cells Through Upregulating Cellular Glucose Metabolism
por: Gao, Sujie, et al.
Publicado: (2020)

Nonphosphorylatable PEA15 mutant inhibits epithelial-mesenchymal transition in triple-negative breast cancer partly through the regulation of IL-8 expression
por: Park, Jihyun, et al.
Publicado: (2021)

Antibody targeted CpG for the immunotherapy of solid tumors
por: Epstein, Alan L, et al.
Publicado: (2015)

The revival of CpG oligonucleotide-based cancer immunotherapies
por: Adamus, Tomasz, et al.
Publicado: (2018)

Downregulation of miR-205 contributes to epithelial–mesenchymal transition and invasion in triple-negative breast cancer by targeting HMGB1–RAGE signaling pathway
por: Wang, Ling, et al.
Publicado: (2019)

A83-01 inhibits TGF-β-induced upregulation of Wnt3 and epithelial to mesenchymal transition in HER2-overexpressing breast cancer cells
por: Wu, Yanyuan, et al.
Publicado: (2017)

FoxM1 promotes epithelial–mesenchymal transition, invasion, and migration of tongue squamous cell carcinoma cells through a c-Met/AKT-dependent positive feedback loop
por: Yang, Huiling, et al.
Publicado: (2018)

Metabolism and accumulation of the lipophilic deoxynucleoside analogs elacytarabine and CP-4126
por: Adema, Auke D., et al.
Publicado: (2011)

Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors
por: Bonde, Anne-Katrine, et al.
Publicado: (2012)

Preservation of methylated CpG dinucleotides in human CpG islands
por: Panchin, Alexander Y., et al.
Publicado: (2016)

Investigation of role of CpG methylation in some epithelial mesenchymal transition gene in a chemoresistant ovarian cancer cell line
por: Alghamian, Yaman, et al.
Publicado: (2022)

Suppressive CpG
por: Van Epps, Heather L.
Publicado: (2005)

Factors to preserve CpG-rich sequences in methylated CpG islands
por: Miyahara, Hiroki, et al.
Publicado: (2015)

Abnormal Flow Conditions Promote Endocardial Fibroelastosis Via Endothelial-to-Mesenchymal Transition, Which Is Responsive to Losartan Treatment
por: Oh, Nicholas A., et al.
Publicado: (2021)

Immunotherapy with CpG-ODN in neoplastic meningitis: A phase I trial
por: Ursu, Renata, et al.
Publicado: (2015)

In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases
por: Arand, Julia, et al.
Publicado: (2012)

CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function
por: Jang, Hyun Sik, et al.
Publicado: (2017)

Methyl-CpG-binding domain 3 inhibits epithelial–mesenchymal transition in pancreatic cancer cells via TGF-β/Smad signalling
por: Xu, Min, et al.
Publicado: (2017)

DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells
por: Xiang, Tingxiu, et al.
Publicado: (2016)

Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models
por: Bergman, Andries M., et al.
Publicado: (2010)

The Role of the CpG Island Methylator Phenotype on Survival Outcome in Colon Cancer
por: Kang, Ki Joo, et al.
Publicado: (2015)

Synthetic HDL Nanoparticles Delivering Docetaxel and CpG for Chemoimmunotherapy of Colon Adenocarcinoma
por: Scheetz, Lindsay M., et al.
Publicado: (2020)

Prediction of CpG-island function: CpG clustering vs. sliding-window methods
por: Hackenberg, Michael, et al.
Publicado: (2010)

CpG Methylation Altered the Stability and Structure of the i-Motifs Located in the CpG Islands
por: Oshikawa, Daiki, et al.
Publicado: (2022)

Nanoparticulate CpG Immunotherapy in RAO‐Affected Horses: Phase I and IIa Study
por: Klier, J., et al.
Publicado: (2015)

CpGIF: an algorithm for the identification of CpG islands
por: Sujuan, Ye, et al.
Publicado: (2008)

Engineering targeted chromosomal amplifications in human breast epithelial cells
por: Springer, Simeon, et al.
Publicado: (2015)

KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer
por: Pei, Lijiao, et al.
Publicado: (2018)

The Effects of O(6)-methyl Guanine DNA-methyl Transferase Promotor Methylation and CpG1, CpG2, CpG3 and CpG4 Methylation on Treatment Response and their Prognostic Significance in Patients with Glioblastoma
por: Yildiz, OG, et al.
Publicado: (2020)

A novel gene expression signature for bone metastasis in breast carcinomas
por: Savci-Heijink, C. Dilara, et al.
Publicado: (2016)

Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple‐negative breast cancer
por: Yamamoto, Mizuki, et al.
Publicado: (2017)

The Control Region of Mitochondrial DNA Shows an Unusual CpG and Non-CpG Methylation Pattern
por: Bellizzi, Dina, et al.
Publicado: (2013)

Evaluation of single CpG sites as proxies of CpG island methylation states at the genome scale
por: Barrera, Víctor, et al.
Publicado: (2012)

Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level
por: Goldsmith, Chloe, et al.
Publicado: (2021)

Cytotoxic T cell depletion with increasing epithelial abnormality in women with benign breast disease
por: Adhikary, Sabina, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7p9a27u3v12djtlt20ofkf0thp