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Identification and Characterization of Plasmin-Independent Thrombolytic Enzymes

RATIONALE: Current thrombolytic agents activate plasminogen to plasmin which triggers fibrinolysis to dissolve thrombi. Since plasmin is a nonspecific proteolytic enzyme, all of the current plasmin-dependent thrombolytics lead to serious hemorrhagic complications, demanding a new class of fibrinolyt...

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Detalles Bibliográficos
Autores principales:	Hassan, Md. Mehedi, Sharmin, Shirina, Kim, Hyeon-Jin, Hong, Seong-Tshool
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861503/ https://www.ncbi.nlm.nih.gov/pubmed/33292062 http://dx.doi.org/10.1161/CIRCRESAHA.120.317245

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