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Botulinum Toxin Type A as a Tool for Correcting Capsular Contracture after Reconstructive Breast Surgery

Capsular contracture is one of the most common complications after breast reconstruction. Surgical treatment is the main option for capsular contracture correction and includes capsulotomy, capsulectomy, and removal/replacement of the affected implant. However, the surgical trauma from reoperation,...

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Autores principales: Zikiryakhodzhaev, Aziz D., Alekseeva, Galina S., Reshetov, Igor V., Starkova, Marianna V., Saribekyan, Eric K., Usov, Fedor N., Vlasova, Maria Yu.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861963/
https://www.ncbi.nlm.nih.gov/pubmed/33552818
http://dx.doi.org/10.1097/GOX.0000000000003372
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author Zikiryakhodzhaev, Aziz D.
Alekseeva, Galina S.
Reshetov, Igor V.
Starkova, Marianna V.
Saribekyan, Eric K.
Usov, Fedor N.
Vlasova, Maria Yu.
author_facet Zikiryakhodzhaev, Aziz D.
Alekseeva, Galina S.
Reshetov, Igor V.
Starkova, Marianna V.
Saribekyan, Eric K.
Usov, Fedor N.
Vlasova, Maria Yu.
author_sort Zikiryakhodzhaev, Aziz D.
collection PubMed
description Capsular contracture is one of the most common complications after breast reconstruction. Surgical treatment is the main option for capsular contracture correction and includes capsulotomy, capsulectomy, and removal/replacement of the affected implant. However, the surgical trauma from reoperation, along with reduced quality of life, in patients with clinically significant capsular contracture has prompted a search for alternative treatment options. The use of the botulinum toxin type A in the treatment of neurological diseases and of keloid scars in aesthetic practice nudged the idea of using the same toxin for the correction of capsular contractures in breast cancer patients. Botulinum toxin type A injection is an easy procedure requiring no anesthesia or inpatient care. The treatment has few side effects. In addition, the injection does not cause sensory loss or dysesthesia. We described a clinical case of the capsular contracture correction using incobotulinumtoxin A. Capsular contracture IV developed 4 months post surgery after long-term lymphorrhea. Radiation therapy was not performed. According to the internal protocol, the patient was advised to undergo incobotulinumtoxin A treatment instead of surgery. Within 1 week after the second injection, all symptoms decreased—specifically, the general shape of the reconstructed breast. Also, the pain syndrome disappeared.
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spelling pubmed-78619632021-02-05 Botulinum Toxin Type A as a Tool for Correcting Capsular Contracture after Reconstructive Breast Surgery Zikiryakhodzhaev, Aziz D. Alekseeva, Galina S. Reshetov, Igor V. Starkova, Marianna V. Saribekyan, Eric K. Usov, Fedor N. Vlasova, Maria Yu. Plast Reconstr Surg Glob Open Case Report Capsular contracture is one of the most common complications after breast reconstruction. Surgical treatment is the main option for capsular contracture correction and includes capsulotomy, capsulectomy, and removal/replacement of the affected implant. However, the surgical trauma from reoperation, along with reduced quality of life, in patients with clinically significant capsular contracture has prompted a search for alternative treatment options. The use of the botulinum toxin type A in the treatment of neurological diseases and of keloid scars in aesthetic practice nudged the idea of using the same toxin for the correction of capsular contractures in breast cancer patients. Botulinum toxin type A injection is an easy procedure requiring no anesthesia or inpatient care. The treatment has few side effects. In addition, the injection does not cause sensory loss or dysesthesia. We described a clinical case of the capsular contracture correction using incobotulinumtoxin A. Capsular contracture IV developed 4 months post surgery after long-term lymphorrhea. Radiation therapy was not performed. According to the internal protocol, the patient was advised to undergo incobotulinumtoxin A treatment instead of surgery. Within 1 week after the second injection, all symptoms decreased—specifically, the general shape of the reconstructed breast. Also, the pain syndrome disappeared. Lippincott Williams & Wilkins 2021-01-25 /pmc/articles/PMC7861963/ /pubmed/33552818 http://dx.doi.org/10.1097/GOX.0000000000003372 Text en Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Zikiryakhodzhaev, Aziz D.
Alekseeva, Galina S.
Reshetov, Igor V.
Starkova, Marianna V.
Saribekyan, Eric K.
Usov, Fedor N.
Vlasova, Maria Yu.
Botulinum Toxin Type A as a Tool for Correcting Capsular Contracture after Reconstructive Breast Surgery
title Botulinum Toxin Type A as a Tool for Correcting Capsular Contracture after Reconstructive Breast Surgery
title_full Botulinum Toxin Type A as a Tool for Correcting Capsular Contracture after Reconstructive Breast Surgery
title_fullStr Botulinum Toxin Type A as a Tool for Correcting Capsular Contracture after Reconstructive Breast Surgery
title_full_unstemmed Botulinum Toxin Type A as a Tool for Correcting Capsular Contracture after Reconstructive Breast Surgery
title_short Botulinum Toxin Type A as a Tool for Correcting Capsular Contracture after Reconstructive Breast Surgery
title_sort botulinum toxin type a as a tool for correcting capsular contracture after reconstructive breast surgery
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861963/
https://www.ncbi.nlm.nih.gov/pubmed/33552818
http://dx.doi.org/10.1097/GOX.0000000000003372
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