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Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula
Rectovaginal fistula, which can arise after an injury to the vaginal canal or rectum, is a troublesome obstacle for patients’ everyday life. In most cases, it can be covered with a local flap, but previous radiation therapy increases the recurrence rate, making it especially difficult to cure. As th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Plastic and Reconstructive Surgeons
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861982/ https://www.ncbi.nlm.nih.gov/pubmed/33503756 http://dx.doi.org/10.5999/aps.2020.01718 |
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author | Kim, Mijung Lew, Dae Hyun Roh, Tai Suk Song, Seung Yong |
author_facet | Kim, Mijung Lew, Dae Hyun Roh, Tai Suk Song, Seung Yong |
author_sort | Kim, Mijung |
collection | PubMed |
description | Rectovaginal fistula, which can arise after an injury to the vaginal canal or rectum, is a troublesome obstacle for patients’ everyday life. In most cases, it can be covered with a local flap, but previous radiation therapy increases the recurrence rate, making it especially difficult to cure. As the application of stromal vascular fraction (SVF) obtained from enzymatically digested autologous adipose tissue has become increasingly common, several reports have advocated its effectiveness for the treatment of refractory wounds. In light of the angiogenic, regenerative characteristics of SVF, it was incorporated as a treatment option in two cases of rectovaginal fistula discussed here. As described in this report, irradiated rectovaginal fistulas in rectal cancer patients were successfully treated with SVF injection, and we suggest SVF as a feasible treatment option for cases of rectovaginal fistula that would otherwise be very difficult to cure. |
format | Online Article Text |
id | pubmed-7861982 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Korean Society of Plastic and Reconstructive Surgeons |
record_format | MEDLINE/PubMed |
spelling | pubmed-78619822021-02-10 Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula Kim, Mijung Lew, Dae Hyun Roh, Tai Suk Song, Seung Yong Arch Plast Surg Extremity/Lymphedema Rectovaginal fistula, which can arise after an injury to the vaginal canal or rectum, is a troublesome obstacle for patients’ everyday life. In most cases, it can be covered with a local flap, but previous radiation therapy increases the recurrence rate, making it especially difficult to cure. As the application of stromal vascular fraction (SVF) obtained from enzymatically digested autologous adipose tissue has become increasingly common, several reports have advocated its effectiveness for the treatment of refractory wounds. In light of the angiogenic, regenerative characteristics of SVF, it was incorporated as a treatment option in two cases of rectovaginal fistula discussed here. As described in this report, irradiated rectovaginal fistulas in rectal cancer patients were successfully treated with SVF injection, and we suggest SVF as a feasible treatment option for cases of rectovaginal fistula that would otherwise be very difficult to cure. Korean Society of Plastic and Reconstructive Surgeons 2021-01 2021-01-15 /pmc/articles/PMC7861982/ /pubmed/33503756 http://dx.doi.org/10.5999/aps.2020.01718 Text en Copyright © 2021 The Korean Society of Plastic and Reconstructive Surgeons This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Extremity/Lymphedema Kim, Mijung Lew, Dae Hyun Roh, Tai Suk Song, Seung Yong Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula |
title | Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula |
title_full | Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula |
title_fullStr | Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula |
title_full_unstemmed | Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula |
title_short | Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula |
title_sort | stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula |
topic | Extremity/Lymphedema |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861982/ https://www.ncbi.nlm.nih.gov/pubmed/33503756 http://dx.doi.org/10.5999/aps.2020.01718 |
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