Neoplastic fibrocytes play an essential role in bone marrow fibrosis in Jak2V617F-induced primary myelofibrosis mice

Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) characterized by clonal myeloproliferation, progressive bone marrow (BM) fibrosis, splenomegaly, and anemia. BM fibrosis was previously thought to be a reactive phenomenon induced by mesenchymal stromal cells that are stimulated by t...

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Detalles Bibliográficos
Autores principales: Ozono, Yoshinori, Shide, Kotaro, Kameda, Takuro, Kamiunten, Ayako, Tahira, Yuki, Sekine, Masaaki, Akizuki, Keiichi, Nakamura, Kenichi, Iwakiri, Hisayoshi, Sueta, Mitsue, Hidaka, Tomonori, Kubuki, Yoko, Yamamoto, Shojiro, Hasuike, Satoru, Sawaguchi, Akira, Nagata, Kenji, Shimoda, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862060/
https://www.ncbi.nlm.nih.gov/pubmed/32472085
http://dx.doi.org/10.1038/s41375-020-0880-3

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