The MC4R p.Ile269Asn mutation confers a high risk for type 2 diabetes in the Mexican population via obesity dependent and independent effects

We investigated the association between the loss-of-function mutation MC4R p.Ile269Asn and T2D risk in the Mexican population. We enrolled 6929 adults [3175 T2D cases and 3754 normal glucose tolerant (NGT) controls] and 994 NGT children in the study. Anthropometric data and T2D-related quantitative...

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Detalles Bibliográficos
Autores principales: Vázquez-Moreno, Miguel, Locia-Morales, Daniel, Valladares-Salgado, Adan, Sharma, Tanmay, Perez-Herrera, Aleyda, Gonzalez-Dzib, Roxana, Rodríguez-Ruíz, Francisco, Wacher-Rodarte, Niels, Cruz, Miguel, Meyre, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862248/
https://www.ncbi.nlm.nih.gov/pubmed/33542413
http://dx.doi.org/10.1038/s41598-021-82728-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862248/
https://www.ncbi.nlm.nih.gov/pubmed/33542413
http://dx.doi.org/10.1038/s41598-021-82728-w

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