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Transcriptional coregualtor NUPR1 maintains tamoxifen resistance in breast cancer cells
To support cellular homeostasis and mitigate chemotherapeutic stress, cancer cells must gain a series of adaptive intracellular processes. Here we identify that NUPR1, a tamoxifen (Tam)-induced transcriptional coregulator, is necessary for the maintenance of Tam resistance through physical interacti...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862277/ https://www.ncbi.nlm.nih.gov/pubmed/33542201 http://dx.doi.org/10.1038/s41419-021-03442-z |