ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer

ABIN-1, also called TNIP1, is an ubiquitin-binding protein that serves an important role in suppressing RIPK1-independent apoptosis, necroptosis, and NF-κB activation. However, the involvement of ABIN-1 in the regulation of RIPK1-dependent apoptosis (RDA) is unknown. In this study, we found that pol...

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Detalles Bibliográficos
Autores principales: Cai, Jiali, Hu, Die, Sakya, Judy, Sun, Tao, Wang, Daoyong, Wang, Lin, Mao, Xiaohua, Su, Zhenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862295/
https://www.ncbi.nlm.nih.gov/pubmed/33542218
http://dx.doi.org/10.1038/s41419-021-03427-y

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