Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment

Clinical response to immunotherapy is closely associated with the immunosuppressive tumour microenvironment (TME), and influenced by the dynamic interaction between tumour cells and lymphatic endothelial cells (LECs). Here, we show that high levels of miR-142-5p positively correlate with indoleamine...

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Detalles Bibliográficos
Autores principales: Zhou, Chenfei, Zhang, Yanmei, Yan, Ruiming, Huang, Lei, Mellor, Andrew L., Yang, Yang, Chen, Xiaojing, Wei, Wenfei, Wu, Xiangguang, Yu, Lan, Liang, Luojiao, Zhang, Dan, Wu, Sha, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862304/
https://www.ncbi.nlm.nih.gov/pubmed/32929219
http://dx.doi.org/10.1038/s41418-020-00618-6

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