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Role of Base Excision Repair Pathway in the Processing of Complex DNA Damage Generated by Oxidative Stress and Anticancer Drugs

Chemical alterations in DNA induced by genotoxic factors can have a complex nature such as bulky DNA adducts, interstrand DNA cross-links (ICLs), and clustered DNA lesions (including double-strand breaks, DSB). Complex DNA damage (CDD) has a complex character/structure as compared to singular lesion...

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Detalles Bibliográficos
Autores principales:	Baiken, Yeldar, Kanayeva, Damira, Taipakova, Sabira, Groisman, Regina, Ishchenko, Alexander A., Begimbetova, Dinara, Matkarimov, Bakhyt, Saparbaev, Murat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862338/ https://www.ncbi.nlm.nih.gov/pubmed/33553154 http://dx.doi.org/10.3389/fcell.2020.617884

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