An evaluation of approaches for rare variant association analyses of binary traits in related samples

Recognizing that family data provide unique advantage of identifying rare risk variants in genetic association studies, many cohorts with related samples have gone through whole genome sequencing in large initiatives such as the NHLBI Trans-Omics for Precision Medicine (TOPMed) program. Analyzing ra...

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Detalles Bibliográficos
Autores principales: Chen, Ming-Huei, Pitsillides, Achilleas, Yang, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862354/
https://www.ncbi.nlm.nih.gov/pubmed/33542345
http://dx.doi.org/10.1038/s41598-021-82547-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862354/
https://www.ncbi.nlm.nih.gov/pubmed/33542345
http://dx.doi.org/10.1038/s41598-021-82547-z

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