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Ratio of the interferon-γ signature to the immunosuppression signature predicts anti-PD-1 therapy response in melanoma

Immune checkpoint inhibitor (ICI) treatments produce clinical benefit in many patients. However, better pretreatment predictive biomarkers for ICI are still needed to help match individual patients to the treatment most likely to be of benefit. Existing gene expression profiling (GEP)-based biomarke...

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Detalles Bibliográficos
Autores principales: Cui, Chuanliang, Xu, Canqiang, Yang, Wenxian, Chi, Zhihong, Sheng, Xinan, Si, Lu, Xie, Yihong, Yu, Jinyu, Wang, Shun, Yu, Rongshan, Guo, Jun, Kong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862369/
https://www.ncbi.nlm.nih.gov/pubmed/33542239
http://dx.doi.org/10.1038/s41525-021-00169-w