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Inhibition of mPGES-1 attenuates efficient resolution of acute inflammation by enhancing CX3CL1 expression

Despite the progress to understand inflammatory reactions, mechanisms causing their resolution remain poorly understood. Prostanoids, especially prostaglandin E(2) (PGE(2)), are well-characterized mediators of inflammation. PGE(2) is produced in an inducible manner in macrophages (Mϕ) by microsomal...

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Detalles Bibliográficos
Autores principales:	Rappl, Peter, Rösser, Silvia, Maul, Patrick, Bauer, Rebekka, Huard, Arnaud, Schreiber, Yannick, Thomas, Dominique, Geisslinger, Gerd, Jakobsson, Per-Johan, Weigert, Andreas, Brüne, Bernhard, Schmid, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862376/ https://www.ncbi.nlm.nih.gov/pubmed/33542207 http://dx.doi.org/10.1038/s41419-021-03423-2

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