Targeting Aurora B kinase with Tanshinone IIA suppresses tumor growth and overcomes radioresistance

Aurora B kinase is aberrantly overexpressed in various tumors and shown to be a promising target for anti-cancer therapy. In human oral squamous cell carcinoma (OSCC), the high protein level of Aurora B is required for maintaining of malignant phenotypes, including in vitro cell growth, colony forma...

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Detalles Bibliográficos
Autores principales: Li, Ming, Liu, Haidan, Zhao, Qin, Han, Shuangze, Zhou, Li, Liu, Wenbin, Li, Wei, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862432/
https://www.ncbi.nlm.nih.gov/pubmed/33542222
http://dx.doi.org/10.1038/s41419-021-03434-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862432/
https://www.ncbi.nlm.nih.gov/pubmed/33542222
http://dx.doi.org/10.1038/s41419-021-03434-z

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