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Targeting Aurora B kinase with Tanshinone IIA suppresses tumor growth and overcomes radioresistance
Aurora B kinase is aberrantly overexpressed in various tumors and shown to be a promising target for anti-cancer therapy. In human oral squamous cell carcinoma (OSCC), the high protein level of Aurora B is required for maintaining of malignant phenotypes, including in vitro cell growth, colony forma...
Autores principales: | Li, Ming, Liu, Haidan, Zhao, Qin, Han, Shuangze, Zhou, Li, Liu, Wenbin, Li, Wei, Gao, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862432/ https://www.ncbi.nlm.nih.gov/pubmed/33542222 http://dx.doi.org/10.1038/s41419-021-03434-z |
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