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Metformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation

Pancreatic ductal adenocarcinoma (PDAC) has poor prognosis due to limited therapeutic options. This study examines the roles of genome-wide association study identified PDAC-associated genes as therapeutic targets. We have identified HNF4G gene whose silencing most effectively repressed PDAC cell in...

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Detalles Bibliográficos
Autores principales:	Wang, Chengcheng, Zhang, Taiping, Liao, Quan, Dai, Menghua, Guo, Junchao, Yang, Xinyu, Tan, Wen, Lin, Dongxin, Wu, Chen, Zhao, Yupei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862466/ https://www.ncbi.nlm.nih.gov/pubmed/32737864 http://dx.doi.org/10.1007/s13238-020-00760-4

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