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Polygonogram with isobolographic synergy for three-drug combinations of phenobarbital with second-generation antiepileptic drugs in the tonic–clonic seizure model in mice

BACKGROUND: Combination therapy consisting of two or more antiepileptic drugs (AEDs) is usually prescribed for patients with refractory epilepsy. The drug–drug interactions, which may occur among currently available AEDs, are the principal criterion taken by physicians when prescribing the AED combi...

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Detalles Bibliográficos
Autores principales:	Łuszczki, Jarogniew J., Podgórska, Dominika, Kozińska, Justyna, Jankiewicz, Marek, Plewa, Zbigniew, Kominek, Mateusz, Żółkowska, Dorota, Florek-Łuszczki, Magdalena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862539/ https://www.ncbi.nlm.nih.gov/pubmed/33025394 http://dx.doi.org/10.1007/s43440-020-00164-5

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