CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes

Generating cardiomyocytes (CMs) from human induced pluripotent stem cells (hiPSCs) has represented a significant advance in our ability to model cardiac disease. Current differentiation protocols, however, have limited use due to their production of heterogenous cell populations, primarily consistin...

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Detalles Bibliográficos
Autores principales: Chirikian, Orlando, Goodyer, William R., Dzilic, Elda, Serpooshan, Vahid, Buikema, Jan W., McKeithan, Wesley, Wu, HaoDi, Li, Guang, Lee, Soah, Merk, Markus, Galdos, Francisco, Beck, Aimee, Ribeiro, Alexandre J. S., Paige, Sharon, Mercola, Mark, Wu, Joseph C., Pruitt, Beth L., Wu, Sean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862643/
https://www.ncbi.nlm.nih.gov/pubmed/33542270
http://dx.doi.org/10.1038/s41598-021-81860-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862643/
https://www.ncbi.nlm.nih.gov/pubmed/33542270
http://dx.doi.org/10.1038/s41598-021-81860-x

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