The nuclear import of the transcription factor MyoD is reduced in mesenchymal stem cells grown in a 3D micro-engineered niche

Smart biomaterials are increasingly being used to control stem cell fate in vitro by the recapitulation of the native niche microenvironment. By integrating experimental measurements with numerical models, we show that in mesenchymal stem cells grown inside a 3D synthetic niche both nuclear transpor...

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Detalles Bibliográficos
Autores principales: Jacchetti, Emanuela, Nasehi, Ramin, Boeri, Lucia, Parodi, Valentina, Negro, Alessandro, Albani, Diego, Osellame, Roberto, Cerullo, Giulio, Matas, Jose Felix Rodriguez, Raimondi, Manuela Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862644/
https://www.ncbi.nlm.nih.gov/pubmed/33542304
http://dx.doi.org/10.1038/s41598-021-81920-2

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