The aptamer BT200 blocks von Willebrand factor and platelet function in blood of stroke patients

The effect of conventional anti-platelet agents is limited in secondary stroke prevention, and their effects are blunted under high shear stress in the presence of increased levels of circulating von Willebrand factor (VWF). VWF is critically involved in thrombus formation at sites of stenotic extra...

Descripción completa

Detalles Bibliográficos
Autores principales: Kovacevic, Katarina D., Greisenegger, Stefan, Langer, Agnes, Gelbenegger, Georg, Buchtele, Nina, Pabinger, Ingrid, Petroczi, Karin, Zhu, Shuhao, Gilbert, James C., Jilma, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862663/
https://www.ncbi.nlm.nih.gov/pubmed/33542410
http://dx.doi.org/10.1038/s41598-021-82747-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862663/
https://www.ncbi.nlm.nih.gov/pubmed/33542410
http://dx.doi.org/10.1038/s41598-021-82747-7

Ejemplares similares