Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults

The role of children in the spread of the SARS-CoV-2 coronavirus has become a matter of urgent debate as societies in the US and abroad consider how to safely reopen schools. Small studies have suggested higher viral loads in young children. Here we present a multicenter investigation on over five t...

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Autores principales: Madera, Sharline, Crawford, Emily, Langelier, Charles, Tran, Nam K., Thornborrow, Ed, Miller, Steve, DeRisi, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862672/
https://www.ncbi.nlm.nih.gov/pubmed/33542262
http://dx.doi.org/10.1038/s41598-021-81934-w
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author Madera, Sharline
Crawford, Emily
Langelier, Charles
Tran, Nam K.
Thornborrow, Ed
Miller, Steve
DeRisi, Joseph L.
author_facet Madera, Sharline
Crawford, Emily
Langelier, Charles
Tran, Nam K.
Thornborrow, Ed
Miller, Steve
DeRisi, Joseph L.
author_sort Madera, Sharline
collection PubMed
description The role of children in the spread of the SARS-CoV-2 coronavirus has become a matter of urgent debate as societies in the US and abroad consider how to safely reopen schools. Small studies have suggested higher viral loads in young children. Here we present a multicenter investigation on over five thousand SARS-CoV-2 cases confirmed by real-time reverse transcription (RT) PCR assay. Notably, we found no discernable difference in amount of viral nucleic acid among young children and adults.
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spelling pubmed-78626722021-02-08 Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults Madera, Sharline Crawford, Emily Langelier, Charles Tran, Nam K. Thornborrow, Ed Miller, Steve DeRisi, Joseph L. Sci Rep Article The role of children in the spread of the SARS-CoV-2 coronavirus has become a matter of urgent debate as societies in the US and abroad consider how to safely reopen schools. Small studies have suggested higher viral loads in young children. Here we present a multicenter investigation on over five thousand SARS-CoV-2 cases confirmed by real-time reverse transcription (RT) PCR assay. Notably, we found no discernable difference in amount of viral nucleic acid among young children and adults. Nature Publishing Group UK 2021-02-04 /pmc/articles/PMC7862672/ /pubmed/33542262 http://dx.doi.org/10.1038/s41598-021-81934-w Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Madera, Sharline
Crawford, Emily
Langelier, Charles
Tran, Nam K.
Thornborrow, Ed
Miller, Steve
DeRisi, Joseph L.
Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults
title Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults
title_full Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults
title_fullStr Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults
title_full_unstemmed Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults
title_short Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults
title_sort nasopharyngeal sars-cov-2 viral loads in young children do not differ significantly from those in older children and adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862672/
https://www.ncbi.nlm.nih.gov/pubmed/33542262
http://dx.doi.org/10.1038/s41598-021-81934-w
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