Cargando…

Endogenous social distancing and its underappreciated impact on the epidemic curve

Social distancing is an effective strategy to mitigate the impact of infectious diseases. If sick or healthy, or both, predominantly socially distance, the epidemic curve flattens. Contact reductions may occur for different reasons during a pandemic including health-related mobility loss (severity o...

Descripción completa

Detalles Bibliográficos
Autores principales: Gosak, Marko, Kraemer, Moritz U. G., Nax, Heinrich H., Perc, Matjaž, Pradelski, Bary S. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862686/
https://www.ncbi.nlm.nih.gov/pubmed/33542416
http://dx.doi.org/10.1038/s41598-021-82770-8
_version_ 1783647341273677824
author Gosak, Marko
Kraemer, Moritz U. G.
Nax, Heinrich H.
Perc, Matjaž
Pradelski, Bary S. R.
author_facet Gosak, Marko
Kraemer, Moritz U. G.
Nax, Heinrich H.
Perc, Matjaž
Pradelski, Bary S. R.
author_sort Gosak, Marko
collection PubMed
description Social distancing is an effective strategy to mitigate the impact of infectious diseases. If sick or healthy, or both, predominantly socially distance, the epidemic curve flattens. Contact reductions may occur for different reasons during a pandemic including health-related mobility loss (severity of symptoms), duty of care for a member of a high-risk group, and forced quarantine. Other decisions to reduce contacts are of a more voluntary nature. In particular, sick people reduce contacts consciously to avoid infecting others, and healthy individuals reduce contacts in order to stay healthy. We use game theory to formalize the interaction of voluntary social distancing in a partially infected population. This improves the behavioral micro-foundations of epidemiological models, and predicts differential social distancing rates dependent on health status. The model’s key predictions in terms of comparative statics are derived, which concern changes and interactions between social distancing behaviors of sick and healthy. We fit the relevant parameters for endogenous social distancing to an epidemiological model with evidence from influenza waves to provide a benchmark for an epidemic curve with endogenous social distancing. Our results suggest that spreading similar in peak and case numbers to what partial immobilization of the population produces, yet quicker to pass, could occur endogenously. Going forward, eventual social distancing orders and lockdown policies should be benchmarked against more realistic epidemic models that take endogenous social distancing into account, rather than be driven by static, and therefore unrealistic, estimates for social mixing that intrinsically overestimate spreading.
format Online
Article
Text
id pubmed-7862686
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-78626862021-02-08 Endogenous social distancing and its underappreciated impact on the epidemic curve Gosak, Marko Kraemer, Moritz U. G. Nax, Heinrich H. Perc, Matjaž Pradelski, Bary S. R. Sci Rep Article Social distancing is an effective strategy to mitigate the impact of infectious diseases. If sick or healthy, or both, predominantly socially distance, the epidemic curve flattens. Contact reductions may occur for different reasons during a pandemic including health-related mobility loss (severity of symptoms), duty of care for a member of a high-risk group, and forced quarantine. Other decisions to reduce contacts are of a more voluntary nature. In particular, sick people reduce contacts consciously to avoid infecting others, and healthy individuals reduce contacts in order to stay healthy. We use game theory to formalize the interaction of voluntary social distancing in a partially infected population. This improves the behavioral micro-foundations of epidemiological models, and predicts differential social distancing rates dependent on health status. The model’s key predictions in terms of comparative statics are derived, which concern changes and interactions between social distancing behaviors of sick and healthy. We fit the relevant parameters for endogenous social distancing to an epidemiological model with evidence from influenza waves to provide a benchmark for an epidemic curve with endogenous social distancing. Our results suggest that spreading similar in peak and case numbers to what partial immobilization of the population produces, yet quicker to pass, could occur endogenously. Going forward, eventual social distancing orders and lockdown policies should be benchmarked against more realistic epidemic models that take endogenous social distancing into account, rather than be driven by static, and therefore unrealistic, estimates for social mixing that intrinsically overestimate spreading. Nature Publishing Group UK 2021-02-04 /pmc/articles/PMC7862686/ /pubmed/33542416 http://dx.doi.org/10.1038/s41598-021-82770-8 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Gosak, Marko
Kraemer, Moritz U. G.
Nax, Heinrich H.
Perc, Matjaž
Pradelski, Bary S. R.
Endogenous social distancing and its underappreciated impact on the epidemic curve
title Endogenous social distancing and its underappreciated impact on the epidemic curve
title_full Endogenous social distancing and its underappreciated impact on the epidemic curve
title_fullStr Endogenous social distancing and its underappreciated impact on the epidemic curve
title_full_unstemmed Endogenous social distancing and its underappreciated impact on the epidemic curve
title_short Endogenous social distancing and its underappreciated impact on the epidemic curve
title_sort endogenous social distancing and its underappreciated impact on the epidemic curve
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862686/
https://www.ncbi.nlm.nih.gov/pubmed/33542416
http://dx.doi.org/10.1038/s41598-021-82770-8
work_keys_str_mv AT gosakmarko endogenoussocialdistancinganditsunderappreciatedimpactontheepidemiccurve
AT kraemermoritzug endogenoussocialdistancinganditsunderappreciatedimpactontheepidemiccurve
AT naxheinrichh endogenoussocialdistancinganditsunderappreciatedimpactontheepidemiccurve
AT percmatjaz endogenoussocialdistancinganditsunderappreciatedimpactontheepidemiccurve
AT pradelskibarysr endogenoussocialdistancinganditsunderappreciatedimpactontheepidemiccurve