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K(ATP) Opener Attenuates Diabetic-Induced Müller Gliosis and Inflammation by Modulating Kir6.1 in Microglia

PURPOSE: This study aimed to determine the effect of pinacidil, a nonselective K(ATP) channel opener, on diabetes-induced retinal gliosis and inflammation. METHODS: Primary and immortalized cell lines of retinal microglia and Müller cells were used to set up a coculture model. In the trans-well syst...

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Detalles Bibliográficos
Autores principales:	Li, Hong, Chen, Donglong, Sun, Wei, Chen, Jiansu, Luo, Chang, Xu, Heping, Ma, Jacey Hongjie, Tang, Shibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2021
Materias:	Retinal Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862730/ https://www.ncbi.nlm.nih.gov/pubmed/33523201 http://dx.doi.org/10.1167/iovs.62.2.3

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