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Quantifying the Stability of Coupled Genetic and Epigenetic Switches With Variational Methods
The Waddington landscape provides an intuitive metaphor to view development as a ball rolling down the hill, with distinct phenotypes as basins and differentiation pathways as valleys. Since, at a molecular level, cell differentiation arises from interactions among the genes, a mathematical definiti...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862759/ https://www.ncbi.nlm.nih.gov/pubmed/33552146 http://dx.doi.org/10.3389/fgene.2020.636724 |