Early Long-Term Memory Impairment and Changes in the Expression of Synaptic Plasticity-Associated Genes, in the McGill-R-Thy1-APP Rat Model of Alzheimer's-Like Brain Amyloidosis

Accruing evidence supports the hypothesis that memory deficits in early Alzheimer Disease (AD) might be due to synaptic failure caused by accumulation of intracellular amyloid beta (Aβ) oligomers, then secreted to the extracellular media. Transgenic mouse AD models provide valuable information on AD...

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Detalles Bibliográficos
Autores principales: Habif, Martín, Do Carmo, Sonia, Báez, María Verónica, Colettis, Natalia Claudia, Cercato, Magalí Cecilia, Salas, Daniela Alejandra, Acutain, María Florencia, Sister, Caterina Laura, Berkowicz, Valeria Laura, Canal, María Pilar, González Garello, Tomás, Cuello, A. Claudio, Jerusalinsky, Diana Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862771/
https://www.ncbi.nlm.nih.gov/pubmed/33551786
http://dx.doi.org/10.3389/fnagi.2020.585873

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