Cargando…
Photopharmacological Manipulation of Mammalian CRY1 for Regulation of the Circadian Clock
[Image: see text] CRY1 and CRY2 proteins are highly conserved components of the circadian clock that controls daily physiological rhythms. Disruption of CRY functions are related to many diseases, including circadian sleep phase disorder. Development of isoform-selective and spatiotemporally control...
Autores principales: | Kolarski, Dušan, Miller, Simon, Oshima, Tsuyoshi, Nagai, Yoshiko, Aoki, Yugo, Kobauri, Piermichele, Srivastava, Ashutosh, Sugiyama, Akiko, Amaike, Kazuma, Sato, Ayato, Tama, Florence, Szymanski, Wiktor, Feringa, Ben L., Itami, Kenichiro, Hirota, Tsuyoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863067/ https://www.ncbi.nlm.nih.gov/pubmed/33464888 http://dx.doi.org/10.1021/jacs.0c12280 |
Ejemplares similares
-
Hypothesis-Driven,
Structure-Based Design in Photopharmacology:
The Case of eDHFR Inhibitors
por: Kobauri, Piermichele, et al.
Publicado: (2022) -
Controlling
the Circadian Clock with High Temporal
Resolution through Photodosing
por: Kolarski, Dušan, et al.
Publicado: (2019) -
Light-Control over Casein Kinase 1δ Activity with Photopharmacology: A Clear Case for Arylazopyrazole-Based Inhibitors
por: Schulte, Albert M., et al.
Publicado: (2022) -
Reversible modulation of circadian time with chronophotopharmacology
por: Kolarski, Dušan, et al.
Publicado: (2021) -
CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy
por: Miller, Simon, et al.
Publicado: (2022)