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Protein disulfide isomerase ERp57 protects early muscle denervation in experimental ALS
Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects motoneurons. Mutations in superoxide dismutase 1 (SOD1) have been described as a causative genetic factor for ALS. Mice overexpressing ALS-linked mutant SOD1 develop ALS symptoms accompanied by histopat...
Autores principales: | Rozas, Pablo, Pinto, Cristina, Martínez Traub, Francisca, Díaz, Rodrigo, Pérez, Viviana, Becerra, Daniela, Ojeda, Patricia, Ojeda, Jorge, Wright, Madison T., Mella, Jessica, Plate, Lars, Henríquez, Juan Pablo, Hetz, Claudio, Medinas, Danilo B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863244/ https://www.ncbi.nlm.nih.gov/pubmed/33541434 http://dx.doi.org/10.1186/s40478-020-01116-z |
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